15 research outputs found
TomograPy: A Fast, Instrument-Independent, Solar Tomography Software
Solar tomography has progressed rapidly in recent years thanks to the
development of robust algorithms and the availability of more powerful
computers. It can today provide crucial insights in solving issues related to
the line-of-sight integration present in the data of solar imagers and
coronagraphs. However, there remain challenges such as the increase of the
available volume of data, the handling of the temporal evolution of the
observed structures, and the heterogeneity of the data in multi-spacecraft
studies.
We present a generic software package that can perform fast tomographic
inversions that scales linearly with the number of measurements, linearly with
the length of the reconstruction cube (and not the number of voxels) and
linearly with the number of cores and can use data from different sources and
with a variety of physical models: TomograPy
(http://nbarbey.github.com/TomograPy/), an open-source software freely
available on the Python Package Index. For performance, TomograPy uses a
parallelized-projection algorithm. It relies on the World Coordinate System
standard to manage various data sources. A variety of inversion algorithms are
provided to perform the tomographic-map estimation. A test suite is provided
along with the code to ensure software quality. Since it makes use of the
Siddon algorithm it is restricted to rectangular parallelepiped voxels but the
spherical geometry of the corona can be handled through proper use of priors.
We describe the main features of the code and show three practical examples
of multi-spacecraft tomographic inversions using STEREO/EUVI and STEREO/COR1
data. Static and smoothly varying temporal evolution models are presented.Comment: 21 pages, 6 figures, 5 table
Reconstructing the 3-D Trajectories of CMEs in the Inner Heliosphere
A method for the full three-dimensional (3-D) reconstruction of the
trajectories of coronal mass ejections (CMEs) using Solar TErrestrial RElations
Observatory (STEREO) data is presented. Four CMEs that were simultaneously
observed by the inner and outer coronagraphs (COR1 and 2) of the Ahead and
Behind STEREO satellites were analysed. These observations were used to derive
CME trajectories in 3-D out to ~15Rsun. The reconstructions using COR1/2 data
support a radial propagation model. Assuming pseudo-radial propagation at large
distances from the Sun (15-240Rsun), the CME positions were extrapolated into
the Heliospheric Imager (HI) field-of-view. We estimated the CME velocities in
the different fields-of-view. It was found that CMEs slower than the solar wind
were accelerated, while CMEs faster than the solar wind were decelerated, with
both tending to the solar wind velocity.Comment: 17 pages, 10 figures, 1 appendi
How to optimize nonlinear force-free coronal magnetic field extrapolations from SDO/HMI vector magnetograms?
The SDO/HMI instruments provide photospheric vector magnetograms with a high
spatial and temporal resolution. Our intention is to model the coronal magnetic
field above active regions with the help of a nonlinear force-free
extrapolation code. Our code is based on an optimization principle and has been
tested extensively with semi-analytic and numeric equilibria and been applied
before to vector magnetograms from Hinode and ground based observations.
Recently we implemented a new version which takes measurement errors in
photospheric vector magnetograms into account. Photospheric field measurements
are often due to measurement errors and finite nonmagnetic forces inconsistent
as a boundary for a force-free field in the corona. In order to deal with these
uncertainties, we developed two improvements: 1.) Preprocessing of the surface
measurements in order to make them compatible with a force-free field 2.) The
new code keeps a balance between the force-free constraint and deviation from
the photospheric field measurements. Both methods contain free parameters,
which have to be optimized for use with data from SDO/HMI. Within this work we
describe the corresponding analysis method and evaluate the force-free
equilibria by means of how well force-freeness and solenoidal conditions are
fulfilled, the angle between magnetic field and electric current and by
comparing projections of magnetic field lines with coronal images from SDO/AIA.
We also compute the available free magnetic energy and discuss the potential
influence of control parameters.Comment: 17 Pages, 6 Figures, Sol. Phys., accepte
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
Expression of the transcription repressor Gfi-1 is required for the maintenance of murine hematopoietic stem cells. In human cells, ectopic expression of Gfi-1 inhibits and RNA interference-mediated Gfi-1 downregulation enhances proliferation and colony formation of p210BCR/ABL expressing cells. To investigate the molecular mechanisms that may explain the effects of perturbing Gfi-1 expression in human cells, Gfi-1-regulated genes were identified by microarray analysis in K562 cells expressing the tamoxifen-regulated Gfi-1-ER protein. STAT 5B and Mcl-1, two genes important for the proliferation and survival of hematopoietic stem cells, were identified as direct and functionally relevant Gfi-1 targets in p210BCR/ABL-transformed cells because: (i) their expression and promoter activity was repressed by Gfi-1 and (ii) when constitutively expressed blocked the proliferation and colony formation inhibitory effects of Gfi-1. Consistent with these findings, genetic or pharmacological inhibition of STAT 5 and/or Mcl-1 markedly suppressed proliferation and colony formation of K562 and CD34+ chronic myelogenous leukemia (CML) cells. Together, these studies suggest that the Gfi-1STAT 5B/Mcl-1 regulatory pathway identified here can be modulated to suppress the proliferation and survival of p210BCR/ABL-transformed cells including CD34+ CML cells
Calibrating the Pointing and Optical Parameters of the STEREO Heliospheric Imagers
The Heliospheric Imager (HI) instruments on the Solar TErrestrial RElations Observatory (STEREO) observe solar plasma as it streams out from the Sun and into the heliosphere. The telescopes point off-limb (from about 4° to 90° elongation) and so the Sun is not in the field of view. Hence, the Sun cannot be used to confirm the instrument pointing. Until now, the pointing of the instruments have been calculated using the nominal preflight instrument offsets from the STEREO spacecraft together with the spacecraft attitude data. This paper develops a new method for deriving the instrument pointing solutions, along with other optical parameters, by comparing the locations of stars identified in each HI image with the known star positions predicted from a star catalogue. The pointing and optical parameters are varied in an autonomous manner to minimise the discrepancy between the predicted and observed positions of the stars. This method is applied to all HI observations from the beginning of the mission to the end of April 2008. For the vast majority of images a good attitude solution has been obtained with a mean-squared deviation between the observed and predicted star positions of one image pixel or less. Updated values have been obtained for the instrument offsets relative to the spacecraft, and for the optical parameters of the HI cameras. With this method the HI images can be considered as “self-calibrating,” with the actual instrument offsets calculated as a byproduct. The updated pointing results and their by-products have been implemented in SolarSoft
The Heliospheric Imagers onboard the STEREO mission
Mounted on the sides of two widely separated spacecraft, the two Heliospheric Imager (HI) instruments onboard NASA’s STEREO mission view, for the first time, the space between the Sun and Earth. These instruments are wide-angle visible-light imagers that incorporate sufficient baffling to eliminate scattered light to the extent that the passage of solar coronal mass ejections (CMEs) through the heliosphere can be detected. Each HI instrument comprises two cameras, HI-1 and HI-2, which have 20° and 70° fields of view and are off-pointed from the Sun direction by 14.0° and 53.7°, respectively, with their optical axes aligned in the ecliptic plane. This arrangement provides coverage over solar elongation angles from 4.0° to 88.7° at the viewpoints of the two spacecraft, thereby allowing the observation of Earth-directed CMEs along the Sun – Earth line to the vicinity of the Earth and beyond. Given the two separated platforms, this also presents the first opportunity to view the structure and evolution of CMEs in three dimensions. The STEREO spacecraft were launched from Cape Canaveral Air Force Base in late October 2006, and the HI instruments have been performing scientific observations since early 2007. The design, development, manufacture, and calibration of these unique instruments are reviewed in this paper. Mission operations, including the initial commissioning phase and the science operations phase, are described. Data processing and analysis procedures are briefly discussed, and ground-test results and in-orbit observations are used to demonstrate that the performance of the instruments meets the original scientific requirements